Guideline Update: Adult Liver Transplantation: Candidate Evaluation-Guideline Update: Adult Liver Transplantation

Guideline Update: Adult Liver Transplantation - Candidate Evaluation

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Video Summary

The new ASLD guidelines reflect major changes in liver transplantation over the past decade and emphasize expanding equitable access to evaluation. Patients with chronic liver disease should be referred after any decompensating event, regardless of MELD score; the appropriate referral threshold without decompensation remains uncertain. Transplantation should be considered for patients with hepatocellular carcinoma without extrahepatic spread. For alcohol-associated liver disease, evaluation should be multidisciplinary, and a fixed period of abstinence should not alone exclude a patient from listing; ongoing support and monitoring are important. The growing prevalence of MASLD highlights the need for careful cardiovascular and comorbidity assessment. The authors also identify transplant oncology and multi-organ transplantation as areas needing further study. They stress that limited high-quality clinical data constrain recommendations and call for well-designed, multicenter research.

Keywords

liver transplantation

ASLD guidelines

equitable access

hepatocellular carcinoma

alcohol-associated liver disease