Basic Research Workshop
Recorded On: 11/13/2016
This workshop will focus on how inducible pluripotent stem cells (iPSCs) can be used to produce liver cells and organoids. These are exciting new tools for experimental hepatology and hold great promise for clinical hepatology. The generation of iPSC-derived liver cells enables studies of the pathophysiology of several human conditions and to explore the effects of new drugs and treatment following a personalized medicine approach. iPSCs can also give rise to multicellular liver organoids with the potential to recapitulate the cellular ecosystem of a human liver, maintain the inter-cellular relationships, and reproduce models of liver disease as experimental models and potential organ-replacement strategies.