The practice of Hepatology is largely consultative in nature, whether evaluating outpatients referred for a variety of abnormal liver enzyme findings or diagnosing and managing critically-ill patients within a team of internists, hospitalists, residents, intensivists, and other healthcare providers.  On any given day, a hepatologist will be confronted with complex patients and dizzying differential diagnoses to be methodically considered.  The aim of this course is to provide insights about state-of-the-art consultative Hepatology attendees that can be applied to daily practice.

2018 Postgraduate Course Enduring Release Dates:

• The Liver Meeting® 2018 Attendees: Immediately following The Liver Meeting®
• AASLD Members: February 1, 2019
• LiverLearning® Subscribers: March 1, 2019

Core Competencies:   

• Patient-centered Care
• Medical Knowledge
• Practice Based Learning and Improvement 
• Interpersonal and Communication Skills
• Professionalism
• Work in Interdisciplinary Teams
• Employ Evidence-based Practice
• Roles/Responsibilities
• Interprofessional Communication
• Teams and Teamwork

Speakers

• Michael W. Fried, MD, FAASLD (Program Chair)
• Cynthia Levy, MD, FAASLD (Program Chair)
• Tse-Ling Fong, MD, FAASLD (Program Chair)
• Naga P. Chalasani, MD, FAASLD (Moderator)
• Rohit Loomba, MD (Moderator)
• Alfred Sidney Barritt, MD, MSCR
• Michael P. Manns, MD
• Heiner Wedemeyer, MD
• Mandana Khalili, MD
• Guadalupe Garcia-Tsao, MD, FAASLD (Moderator)
• Oren K. Fix, MD, MSc, FAASLD (Moderator)
• Kymberly Watt, MD
• Andres Cardenas, MD, MMSc, PhD, FAASLD
• Steven L. Flamm, MD
• Rajiv Jalan, MD, PhD, FRCP, FRCPE, FAASLD
• Vijay Shah, MD
• Laura M. Kulik, MD (Moderator)
• K. Rajender Reddy, MD, FAASLD (Moderator)
• Christopher L. Bowlus, MD, FAASLD
• Paul Y. Kwo, MD, FAASLD
• Lewis R. Roberts, MBChB, PhD, FAASLD
• Paul C. Adams, MD, FAASLD
• Mindie H. Nguyen, MD, MAS, FAASLD
• Robert S. Brown, MD, MPH, FAASLD (Moderator)
• Estella M. Alonso, MD, FAASLD (Moderator)
• Nancy Reau, MD, FAASLD
• Keyur Patel, MD
• Michael B. Fallon, MD, FAASLD
• Elizabeth Rand, MD
• Patrick S. Kamath, MD

Copyright: All faculty in this activity have given their permission for publication ©2018 AASLD.

Session I: Morning Routine

MODERATORS: Naga P. Chalasani, MD, FAASLD and Rohit Loomba, MD

8:00 - 8:10 AM                                                                   A Hectic Day in the Life of a Hepatology Consultant

                                                                                                Welcome/Qualities of a Valued Consultant

8:10 - 8:30 AM                                                                   Abnormal Liver Enzymes in a Patient with Diabetes

                                                                                                Alfred Sidney Barritt, MD, MSCR

8:30- 8:50 AM                                                                    Hepatitis C in a 23-year-old who Injects Drugs

                                                                                                Michael P. Manns, MD

8:50 - 9:10 AM                                                                   Abnormal Liver Enzymes and Recurrent UTI in a 67-year-old Woman

                                                                                                Heiner Wedemeyer, MD

9:10 – 9:30 am                                                                  HBV/HCV Coinfection in a Pregnant Woman

                                                                                                Mandana Khalili, MD

9:30 – 9:50 am                                                                  Break

Session II: Rounds in the MICU

MODERATORS: Guadalupe Garcia-Tsao, MD, FAASLD and Oren K. Fix, MD, MSc, FAASLD 

9:50 - 10:10 AM                                                                Fever and Elevated Liver Enzymes in a Liver Transplant Recipient

                                                                                                Kymberly Watt, MD

10:10 - 10:30 AM                                                              Massive GI Bleeding in a Patient with Cirrhosis: What’s New?

                                                                                                Andres Cardenas, MD, MMSc, PhD, FAASLD

10:30 - 10:50 AM                                                              Altered Mental Status in a Patient with Refractory Ascites

                                                                                                Steven L. Flamm, MD

10:50 – 11:10 AM                                                             Acute Liver Failure in a 26-year-old Woman

                                                                                                Rajiv Jalan, MD, PhD, FRCP, FRCPE, FAASLD

11:10 - 11:30 AM                                                              Jaundice and Renal Failure in a Patient with Alcoholic Cirrhosis

                                                                                                Vijay Shah, MD

11:30 - 11:40 AM                                                              Break

11:40 - 1:05 PM                                                                Intermission/Meet-the-Professor Luncheons

Session III: Meanwhile, Back in the Office…

MODERATORS: Laura M. Kulik, MD and K. Rajender Reddy, MD, FAASLD

1:05 - 1:25 PM                                                                   Cholestatic Liver Abnormalities in a 52-year-old African American Woman

                                                                                                Christopher L. Bowlus, MD, FAASLD

1:25 – 1:45 pm                                                                  Multiple Liver Masses in a 42-year-old Woman Advances in the Diagnosis of Hepatobiliary Neoplasia

                                                                                                Paul Y. Kwo, MD, FAASLD

1:45 – 2:05 pm                                                                  A 1.9 cm HCC in a Patient with HCV Cirrhosis

                                                                                                Lewis R. Roberts, MBChB, PhD, FAASLD

2:05 – 2:25 pm                                                                  “My Brother Was Just Told He Had Too Much Iron in His Blood”

                                                                                                Paul C. Adams, MD, FAASLD

2:25 – 2:45 pm                                                                  A Patient with Crohn’s Disease and HBcAb+

                                                                                                Mindie H. Nguyen, MD, MAS, FAASLD

2:45 – 3:05 pm                                                                  Break

Session IV: Exploring Other Units at Dusk

MODERATORS: Robert S. Brown, MD, MPH, FAASLD and Estella M. Alonso, MD, FAASLD

3:05 – 3:25 pm                                                                  Hyperbilirubinemia in Labor and Delivery

                                                                                                Nancy Reau, MD, FAASLD

3:25 – 3:45 pm                                                                  Hyperbilirubinemia in a Patient after Bone Marrow Transplant

                                                                                                Keyur Patel, MD

3:45 – 4:05 pm                                                                  A 60-year-old in CCU with Jaundice

                                                                                                Michael B. Fallon, MD, FAASLD

4:05 – 4:25 pm                                                                  A 14-year-old Child s/p Fontan Procedure with Liver Abnormalities

                                                                                                Elizabeth Rand, MD

4:25 – 4:45 pm                                                                  Acute Right Upper Quadrant Pain in a Patient with Cirrhosis

                                                                                                Patrick S. Kamath, MD

4:45 – 5:00 pm                                                                 Wrap Up

Upon completion of this activity, participants will be able to:

• Differentiate presentations of complex liver diseases across different patient populations
• Apply best practices to diagnose and manage inpatients and outpatients with complex liver disease
• Communicate therapeutic recommendations to multiple healthcare providers encompassing the extended care team

Hepatologists   

Gastroenterologists       

Nurses

Nurse Practitioners        

Pharmacists

Physician Assistants       

Transplant Coordinators

Surgeons            

Fellows/Trainees

Satisfactory completion 

Participants must pass a post-test with a score of 70% or higher and complete an evaluation to receive a certificate of completion.  If you are seeking continuing education credit for a specialty not listed below, it is your responsibility to contact your licensing/certification board to determine course eligibility for your board requirement.   

CME 

Accreditation Statement The American Association for the Study of Liver Diseases (AASLD) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation AASLD designates this enduring activity for a maximum of 6.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.  

Maintenance of Certification

American Board of Internal Medicine (ABIM) MOC Statement

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 6.75 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

American Board of Pediatrics (ABP) MOC Statement

Successful completion of this CME activity, which includes participation in the activity, with individual assessments of the participation and feedback to the participant, enables the participant to earn 6 MOC points in the American Board of Pediatrics (ABP) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABP MOC credit.

MOC Points Process 

• Physicians seeking MOC points must complete the CME evaluation in addition to viewing all of the presentation(s) and successfully passing the post-test(s) for each module with a score of 70% or better. MOC completions are collected on the 15th of each month and submitted to the ABIM and/or ABP by the last day of the month.
• Claiming of CME credits for the live course can be completed via The Liver Meeting® app or on AASLD's online CME claiming page.
• To claim MOC for attending the live 2018 Postgraduate Course, please visit the 2018 Postgraduate Course MOC activity.

Faculty, Planner and AASLD Staff Disclosures

This live educational activity has been planned in accordance with AASLD and ACCME Standards of Commercial Support by members of the AASLD Postgraduate Course faculty and the following planning committees: AASLD Education Committee, Scientific Program Committee, and the Governing Board.

As an accredited provider, AASLD requires individuals involved in the planning of continuing medical education (CME) activities to disclose all financial relationships, including those of their spouse or partner, with a commercial interest within the past 12 months.  A commercial interest is defined as any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on, patients.  All conflicts of interest are resolved prior to participation.

Statement on off-label and investigational use: Speakers are asked to make a reasonable effort to identify during their presentation any discussion of off-label or investigative use or application of a product or device. Financial disclosures will appear at the beginning of each session and are provided below:

Postgraduate Course Faculty Disclosures

Paul C. Adams, MD, FAASLD

Consulting: Protagonist Therapeutics

Alfred Sidney Barritt IV, MD, MSCR

Advisory Committee or Review Panel: Target Pharmasolutions

Consulting: Dova Pharmaceuticals

Speaking and Teaching: SC Liver Research Consortium

Christopher L Bowlus, MD, FAASLD

Advisory Committee or Review Panel: BMS, Contatus, Cymabay

Consulting: Eli Lilly, BiomX

Grant/Research Support: TARGET Pharmasolutions, JKB Taiwan, Genkyotex, Takeda, Allergan, GSK, Arena, Gilead, Cymabay, Intercept Pharmaceuticals, Novartis, Eli Lilly

Andres Cardenas, MD, MMSc, PhD, FAASLD

Board Membership: Liver Transplantation Journal

Consulting: UptoDate

Grant/Research Support: Boston Scientifi

Michael B. Fallon, MD, FAASLD

Nothing to Disclose

Steven L. Flamm, MD

Consulting: Gilead, Abbvie, Merck, Salix, Intercept, Dova, Shonogi

Grant/Research Support: Gilead, Abbvie, Intercept

Rajiv Jalan, MD, PhD, FRCP, FRCPE, FAASLD

Consulting: Yaqrt Ltd

Grant/Research Support: Ocera Therapeutics Inc.

Patrick S Kamath, MD

Nothing to Disclose

Mandana Khalili, MD

Grant/Research Support: Gilead Sciences, Intercept Pharmaceuticals

Paul Yien Kwo, MD, FAASLD

Advisory Committee or Review Panel: Abbvie, BMS, Gilead, Merck, Shionogi, Dova, Durect, Janssen

Grant/Research Support: Abbvie, Gilead, Aurora, La Jolla Pharmaceuticals

Speaking and Teaching: Merck

Stock Shareholder: Durect

Michael P. Manns, MD

Advisory Committee or Review Panel: MSD - Merck Sharp & Dome, Abbvie, Novartis, Gilead, Bristol-MyersSquibb

Consulting: AbbVie, Gilead, Curevac, Eiger, Enyo Pharma, Falk Foundation, Intercept, Janssen, Medgenics, MSD - Merck, Novartis, GedeonRichter, Roche, Allergan, Preglem

Grant/Research Support: AbbVie, Gilead, Eiger, Intercept, J

Mindie H. Nguyen, MD, MAS, FAASLD

Advisory Committee or Review Panel: Gilead

Consulting: Spring Bank, Norvatis

Grant/Research Support: Gilead, B K Kee Foundation, NCI

Keyur Patel, MD

Advisory Committee or Review Panel: Gilead Sciences, Merck

Elizabeth Rand

Nothing to Disclose

Nancy Reau, MD, FAASLD

Nothing to Disclose

Lewis R. Roberts, MBChB, PhD, FAASLD

Advisory Committee or Review Panel: Bayer, Exact Sciences, TAVEC, Inc

Grant/Research Support: Gilead Sciences, Wake Diagnostics, Ariad Pharmaceuticals, BTG International, RedHill BioPharma

Vijay Shah, MD

Advisory Committee or Review Panel: Novartis Pharmaceuticals, Merck Research Laboratories, Afimmune, Ltd, Durect Corporation

Kymberly Watt, MD

Grant/Research Support: Gilead, Intercept

Heiner Wedemeyer, MD

Advisory Committee or Review Panel: Norgine, MSD, Janssen, Roche Diagnostic

Board Membership: Abbvie, Gilead

Consulting: Abbott, BMS, Eiger, MyrGmbH

Grant/Research Support: Abbott, BMS, Gilead, Roche Diagnsotics

Speaking and Teaching: Abbvie, Abbott, BMS, Gilead, Falk, Norgine, MSD

Planner Disclosures

Gavin E. Arteel, PhD, FAASLD (Scientific Program Committee)

Nothing to Disclose

Gyorgy Baffy, MD, PhD, FAASLD (Education Committee)

Nothing to Disclose

Jasmohan S. Bajaj, MD, MSc, FAASLD (Education Committee)

Consulting: Valeant, Norgine, and Abbott

Grant/Research Support: Salix, Grifols

Ramon Bataller, MD, PhD (Education Committee)

Speaking and Teaching: Echosens

Alex Befeler, MD (Scientific Program Committee)

Advisory Committees or Review Panels: Bayer, Gilead

Grant/Research Support: Mallinckrodt, Sillajen

Stock Shareholder: Amgen, Gilead

Jorge A. Bezerra, MD, FAASLD (Education Committee and Governing Board)

Grant/Research Support: Gilead, Molecular Genetics Laboratory, CHMC, Shier

Kyle E. Brown, MD, FAASLD (Education Committee)

Nothing to Disclose

Kimberly A. Brown, MD, FAASLD (Governing Board and Scientific Program Committee)

Advisory Committees or Review Panels: AbbVie, Bristol-Myers Squibb, CLDF, Gilead, Janssen, Merck

Grant/Research Support: AbbVie, Duke medical research, Gilead, Janssen, Merck, Novartix

Speaking and Teaching: CLDF

Elizabeth M. Brunt, MD, FAASLD (Education Committee)

Advisory Committees or Review Panels: Gilead

Andres Cardenas, MD, PhD, FAASLD (Education Committee)

Advisory Committees or Review Panels: Gilead

Amanda J. Chaney, DNP, ARNP, FNP-BC (Education Committee)

Nothing to Disclose

Raymond T. Chung, MD, FAASLD (Governing Board)

Advisory Committees or Review Panels: Alnylam

Grant/Research Support: AbbVie, Bristol-Myers Squibb, Boehringer Ingelheim, Gilead, Janssen, Merck

Mark J. Czaja, MD, FAASLD (Governing Board)

Consulting: Verlyx Pharma Inc.

Michael W. Fried, MD, FAASLD (Governing Board and Scientific Program Committee)

Consulting: AbbVie, Bristol-Myers Squibb, Gilead, Merck, TARGET PharmaSolutions

Grant/Research Support: AbbVie, Bristol-Myers Squibb, Gilead, Merck

Stock Shareholder: TARGET PharmaSolutions

Julie Heimbach, MD, FAASLD (Governing Board)

Nothing to Disclose

Patrick M. Horne, MSN, ARNP, FNP-BC (Scientific Program Committee)

Advisory Committees or Review Panels: AbbVie, Bristol-Myers Squibb, Chronic Liver Disease Foundation, Gilead Sciences, Merck

Wikrom Karnsakul, MD (Education Committee)

Nothing to Disclose

Andrew P. Keaveny, MD, FAASLD (Education Committee and Scientific Program Committee)

Independent Contractor: UpToDate Inc

Cynthia Levy, MD (Scientific Program Committee)

Advisory Committees or Review Panels: Target Pharmasolutions

Board Membership: Liver Transplantation

Consulting: Intercept, Novartis

Grant/Research Support: CymaBay, Gilead, Intercept, NGM, Novartis, Tobira

Speaking and Teaching: Medscape

Keith D. Lindor, MD, FAASLD (Governing Board)

Advisory Committees or Review Panels:  Intercept, Shire

Anna S. Lok, MD, FAASLD (Governing Board and Scientific Program Committee)

Grant/Research Support: Bristol-Myers Squibb, Gilead, Target Solutions

Bruce A Luxon, MD, PhD, FAASLD (Governing Board)

Nothing to Disclose

John C. Magee, MD (Scientific Program Committee)

Nothing to Disclose

Mitchell A. Mah'moud, MD, FAASLD (Education Committee)

Nothing to Disclose

Richard A. Manch, MD, FAASLD (Education Committee)

Speaking and Teaching:  Salix, Bayer, Gilead, AbbVie, Intecept

Lopa Mishra, MD, FAASLD (Governing Board)

Nothing to Disclose

David C. Mulligan, MD, FAASLD (Education Committee)

Nothing to Disclose

Mary K. Panther, BSN, RN, CGRN (Education Committee)

Stock Shareholder: Merck

K. Gautham Reddy, MD, FAASLD (Scientific Program Committee)

Advisory Committees or Review Panels: Gilead, Intercept

Grant/Research Support: Genfit, Intercept, Merck

Speaking and Teaching: Intercept

Ronald J. Sokol, MD, FAASLD (Governing Board and Scientific Program Committee)

Consulting: Alexion, Alnylam, Retrophin

Grant/Research Support: FFF Enterprises, Giliad, Shire/Lumena

Grace L. Su, MD, FAASLD (Education Committee)

Nothing to Disclose

Ayako Suzuki, MD, PhD, MSc (Education Committee)

Nothing to Disclose

Lisa B. VanWagner, MD, MSc (Education Committee)

Grant/Research Support: Novartis

Speaking and Teaching: Salix

Steven A. Weinman, MD, PhD, FAASLD (Education Committee)

Nothing to Disclose

Maria L. Yataco, MD (Education Committee)

Grant/Research Support: Genfit/Intercept

AASLD Staff Disclosures

Amy D'Amato

Nothing to Disclose

Katie Duggan

Nothing to Disclose

Steven Echard, IOM, CAE

Nothing to Disclose

Stephanie Grimsby

Nothing to Disclose

Jessica Jessop

Nothing to Disclose

Janeil C. Klett

Nothing to Disclose

Denise Seise

Nothing to Disclose