2017 Global Forum: The Global Burden of Non-alcoholic Fatty Liver Disease

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Recorded On: 10/23/2017

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NAFLD affects 24% of the adult population worldwide. Additionally, about 10% of children and adolescents may have NAFLD. NAFLD is closely associated with type 2 diabetes and obesity. A proportion of subjects with NAFLD and non-alcoholic steatohepatitis (NASH) can develop progressive liver disease, cirrhosis and liver cancer. There are extensive efforts to develop non-invasive tests for NASH. Although no approved therapeutic options for NASH are yet available, a large number of clinical trials are underway. This forum will review, in all pertinent regions of the world, the current state of NAFLD with regard to its clinical and epidemiologic burden and discuss knowledge gaps, unmet needs and current clinical practice.  A secondary focus will be to foster global collaboration and exchange to reach a common objective to improve patient outcomes, decrease disease burden by NAFLD and how to prevent and treat NAFLD throughout the world.

Zobair M. Younossi

Zobair M. Younossi, MD, MPH, FAASLD is the President of Inova Medicine, Inova Health System as well as Professor and Chairman of the Department of Medicine at Inova Fairfax Medical Campus in Falls Church, Virginia. He is also Chair of Clinical Research at the same institution. Dr. Younossi earned his medical degree from the University of Rochester School of Medicine and Dentistry in Rochester, NY and completed his residency in internal medicine with a fellowship in gastroenterology and hepatology at Scripps Clinic and Research Foundation in La Jolla, California. He initially served as Staff Hepatologist and Senior Researcher at the Cleveland Clinic Foundation in Cleveland, Ohio before establishing the Center for Liver Diseases at Inova Fairfax Hospital, which is now renowned for research related to outcomes research in liver disease and clinical, health services and translational research in non-alcoholic fatty liver disease (NAFLD). He has served as Vice President of Research for Inova Health System and currently serves as its Chair of Research.

 Over the past three decades, Dr. Younossi has pioneered research in NAFLD and has been a leader in the field of patient-reported outcomes (PROs), economic assessment and other areas of outcomes research in liver disease. He leads a number of international efforts related to NAFLD and PROs in liver disease though global collaborations, including the Chair of Global NASH Council and the Global Liver and NASH Registries. Dr. Younossi has authored over 590 articles, 3 books, 6 journal supplements, over 25 book chapters and over 900 abstracts at the international scientific meetings. 

Frank Tacke

Barjesh C. Sharma

Marco Arrese

Hisham R. El Khayat

Miriam B. Vos

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