The Liver Meeting® 2018 ePosters: Human Cholestatic and Autoimmune Liver Diseases
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LB-26: Effect of Seladelpar on Pruritus in Primary Biliary Cholangitis: 26-Week Analysis of an Ongoing International, Randomized, Dose Ranging Phase 2 StudyAuthors: Pol Boudes, Andreas KremerYou must log in to access content.
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1091: SECs undergo partial EndMT Notch-dependently to deposit perisinusoidal ECM in liver fibrosisAuthor: Lin WangYou must log in to access content.
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1897: Concentration of Biliary Extracellular Vesicles Discriminates between Dominant Strictures in Primary Sclerosing Cholangitis and Cholangiocellular CarcinomaAuthors: Thomas Worst, Peter Sauer, Karl Heinz Weiss, Daniel Gotthardt, Christian Rupp, Peter Schirmacher, Benjamin GöppertYou must log in to access content.
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1898: Safety and Efficacy of Seladelpar in Primary Biliary Cholangitis Patients with CirrhosisAuthors: Christopher Bowlus, Gideon Hirschfield, Bruce Bacon, Joseph Odin, Michael Galambos, Stephen Harrison, Gianni Amato, Alexandra Steinberg, Scott Rosenbusch, Sandrin Bergheanu, Pol BoudesYou must log in to access content.
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1900: Impact of Geographical Region on Death or Transplantation and on Malignancy in Primary Sclerosing Cholangitis – a Multicenter Retrospective Study of the International PSC Study Group (IPSCSG)Authors: Tobias Weismüller, Aliya Gulamhusein, Brian Juran, Cyriel Ponsioen, Palak Trivedi, Annika Bergquist, Atsushi Tanaka, Christian Rupp, Martti Farkkila, Alejandra Villamil, Hanns-Ulrich Marschall, Douglas Thorburn, Rinse Weersma, Johan Fevery, Tobias Müller, Olivier Chazouilleres, Ehud Zigmond, Sven Almer, Stephen Pereira, Cynthia Levy, Xiong Ma, Andrew Mason, Christopher Bowlus, Annarosa Floreani, Emina Halilbasic, Kidist Yimam, Piotr Milkiewicz, Ulrich Beuers, Dep Huynh, Albert Pares, Christine Manser, Sunil Taneja, George Dalekos, Bertus Eksteen, Pietro Invernizzi, Christian Strassburg, Christoph Schramm, Michael Manns, Bettina Hansen, Kirsten Boberg, Christoph Berg, Gabi Kirchner, Konstantinos Lazaridis, Gideon Hirschfield, Henrike Lenzen, Michael Trauner, Trine FolseraasYou must log in to access content.
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1903: Primary Sclerosing Cholangitis Is Characterised By Altered Microbiota of the Bile Fluid Associated to an Altered Bile Acid Composition: Results of a Prospective Single Centre StudyAuthors: Timur Liwinski, Roman Zenouzi, Clara John, Hanno Ehlken, Malte C. Rühlemann, Corinna Bang, Femke A. Heinsen, Marcus Kantowski, Stefan Groth, Guido Schachschal, Thomas Rösch, Ansgar Lohse, Jörg Heeren, Andre Franke, Christoph SchrammYou must log in to access content.
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1906: Does the Beneficial Antipruritic Effect of Bezafibrate in Primary Biliary Cholangitis Depend on Autotaxin Activity?Authors: Andreas Kremer, Aline Le Cleac'h, Katharina Wolf, Christophe Corpechot, Olivier Chazouilleres, Raoul Poupon, Sara Lemoinne, Alexandra Rousseau, Luc De Chaisemartin, Sylvie Chollet-Martin, Dominique Rainteau, Lydie HumbertYou must log in to access content.
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1907: LIVER Stiffness Measurement (LSM) By 2D-Shear Wave Elastography (2D-SWE) in Patients with Primary Biliary Cholangitis (PBC): Correlation with HistologyAuthors: Emanuel Manesis, Maria Schina, Irene Vafiadis, Ilias Gatos, John Theotokas, Pavlos Zoumpoulis, Ioanna Delladetsima, Dina TiniakosYou must log in to access content.
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1912: Defining Disease Severity and Measuring Progression in Primary Sclerosing Cholangitis (PSC): A Comparison of the Disease Severity Index (DSI) from the Hepquant Shunt Test with Serum Alkaline Phosphatase (Alk Phos)Authors: Steve Helmke, Gregory EversonYou must log in to access content.
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1915: Increased Secretin (Sct)-Dependent MicroRNA-125b/TGF-β1/VEGF-A Signaling Promotes Biliary and Liver Damage in a Mouse Model of Early Stage Primary Biliary Cholangitis (PBC)Authors: Lindsey Kennedy, Heather Francis, Juliet Venter, Nan Wu, Konstantina Kyritsi, Tianhao Zhou, Pietro Invernizzi, Fanyin Meng, Francesca Bernuzzi, Shannon Glaser, Gianfranco Alpini, Eugenio Gaudio, Paolo Onori, Antonio FranchittoYou must log in to access content.
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1917: Multi-Parametric MRI in a Heterogeneous Liver Disease: Cross-Sectional Evaluation of a Cohort of Patients with PSCAuthors: Katherine Arndtz, James Hodson, Peter Eddowes, Matthew Kelly, Andrea Dennis, Martine Fiore, Rajarshi Banerjee, Stefan Neubauer, Gideon HirschfieldYou must log in to access content.
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1920: Risk Factors for Transplant-Free Survival in Chinese Patients with Primary Biliary Cholangitis Receiving Ursodeoxycholic Acid: A Cohort of 732 Patients Followed up to 18.3 Years.Authors: Sha Chen, Weijia Duan, Jidong Jia, Hong You, Xiaojuan Ou, Hong MaYou must log in to access content.
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1923: A Real World Experience of Obeticholic Acid (OCA) Therapy in Patients with Primary Biliary Cholangitis (PBC) Treated in a Tertiary Care Liver CenterAuthors: Kidist Yimam, Saba Gebremedhin, Jennifer Guy, Richard Frederick, Timothy Davern, Edward Holt, Stewart Cooper, Courtney Sherman, Raphael Merriman, Adil Wakil, Chanda HoYou must log in to access content.
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1925: The UK-PBC Audit of Real-World Obeticholic Acid Use in Patients with Primary Biliary Cholangitis (PBC)Authors: Palak Trivedi, Gideon Hirschfield, Douglas Thorburn, Aileen Marshall, Richard Aspinall, Alison Dimmer, Jacqueline Swabe, Theresa Hydes, Salim Khakoo, Elizabeth Williams, Felix Cheng, Becky Yu, Amine Benmassaoud, Yannis Kallis, Bellinda Smith, Imran Patanwala, Julie Barr, Stephen Ryder, Tom Ellis, Anne Mccune, Lynsey Corless, Jennifer Hayden, David Jones, Zohur Miah, Jessica Dyson, George MellsYou must log in to access content.
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1926: Antibodies to gp210 and Understanding Risk in Patients with Primary Biliary CholangitisAuthors: Debashis Haldar, Ashnila Janmohamed, Tim Plant, Matthew Davidson, Hannah Norman, Emily Russell, Olivia Serevina, Kenneth Chung, Kashif Qamar, Bridget Gunson, Alex Richter, Gideon HirschfieldYou must log in to access content.
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1930: Prediction of Mortality Risk in Decompensated Cirrhosis Due to Primary Biliary CholangitisAuthors: Aparna Goel, Allison Kwong, Ajitha Mannalithara, W. Ray Kim, Cynthia Feng, Uchenna IloejeYou must log in to access content.
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1931: Hepatic Safety Overview of Obeticholic Acid for the Treatment of Patients with Primary Biliary CholangitisAuthors: Paul Pockros, Mitchell Shiffman, Christopher Bowlus, Arun Sanyal, Frederik Nevens, Richard Pencek, David Shapiro, Amrik Shah, Leigh MacConellYou must log in to access content.
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1934: Magnetic Resonance Cholangiography and Biochemical Predictive Criteria of Response to Endoscopic Treatment of Severe Biliary Strictures in Patients with Primary Sclerosing CholangitisAuthors: Olivier Chazouilleres, Nora Cazzagon, Christophe Corpechot, Sanaa El Mouhadi, Edouard Chambenois, Benoit Desaint, Ulrikka Chaput, Lionel Arrivé, Sara LemoinneYou must log in to access content.
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1937: Predictive Factors Related to Treatment Failure with Ursodeoxycholic Acid in Patients with Primary Biliary CholangitisAuthors: Fatima Higuera de la Tijera, Maria Díaz-Castro, Karen Soto-Martínez, Alfredo Servín-Caamaño, Antonio Cruz-Estrada, Elvira Alexanderson-Rosas, José Pérez-HernándezYou must log in to access content.
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1938: Efficacy of Humanized Anti-Human CD20 on Early Stage Murine Autoimmune Cholangitis Using Human CD20 and Fcγr Expressing DnTGFβRII MiceAuthors: Patrick Leung, Guo-Xiang Yang, M Gershwin, Weici Zhang, Yuki Moritoki, Koichi Tsuneyama, Yuka Nakamura, Kentaro Kikuchi, Akira Shiota, Zhe-Xiong Lian, Shigeharu Ueki, Masahide Takeda, Ayumi Omokawa, Tomoo Saga, Akiko Saga, Daisuke Watanabe, Masahito Miura, Yoshiyuki Ueno, Atsushi Tanaka, Makoto Hirokawa, Yoshiyuki OhsugiYou must log in to access content.
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