The purpose of this webinar is to present strategies to approach patient and family communication near the end-of-life in the setting of advanced liver disease with a focus on issues related to equity, diversity and inclusion. Patients with advanced liver disease experience high symptom burden, emotional distress, and prognostic uncertainty which makes them particularly vulnerable to suboptimal end-of-life care. In addition, prior work from other serious illnesses has highlighted the influence of cultural background including race, ethnicity, religion, sexual orientation, gender and other forms of identity on patients’ end-of-life care experiences and outcomes. In this webinar we will present a series of case scenarios that highlight the importance of approaching end-of-life communications with cultural humility and strategies to develop patient- and family-centered communication skills that acknowledge their voices, concerns, values, and lived experiences. The webinar will include a panel session, case-based presentations, and audience questions and discussion. The panel will consist of physicians with professional expertise that includes hepatology, palliative care, health services research, and health disparities research, and the intended audience is clinicians who provide care to people with liver diseases and their families and informal caregivers.