Coagulation disorders in patients with cirrhosis present challenging situations for clinical providers. This one hour webinar will summarize the knowledge behind coagulation disorders in patients with cirrhosis, including the mixed and thrombosis prone model, limitations in current tests of hemostasis, and the dangers of excessive transfusion. Using practical clinical vignettes, learners will gain understanding of best practice to manage these difficult coagulation situations, including in practice settings where colleagues in hospital medicine and interventional radiology may have different approaches. Vignettes will include an outpatient cirrhotic patient with portal vein thrombosis, an inpatient cirrhotic requiring paracentesis, and an inpatient cirrhotic in the intensive care unit with renal failure and spontaneous mucosal bleeding.