The Liver Meeting 2024 - Debrief Sessions - Spanish-Basic Science Debrief Session

Video Transcription

Video Summary

The Liver Meeting Debrief Session Two, moderated by Dr. Carla Brady and Dr. Debbie Shawcross, presented six exciting discussion segments focusing on key advances in liver disease research. Dr. Yaron Rotman from NIDDK highlighted notable studies in basic science, including research on portal hypertension, hepatic congestion and fibrosis, hepatocellular carcinoma, alcohol-associated liver disease, and novel mouse models simulating acute liver damage. These explorations revealed potential therapeutic targets and enhanced understanding of liver pathology. Key findings included potential uses for VCAM-1 inhibition in fibrosis management, insights into immune evasion in recurrent liver cancer, and the role of BTK inhibitors in ameliorating alcohol-associated hepatitis. Additionally, research suggested DPP-4 inhibitors might boost immune responses to liver tumor treatments and showcased a promising humanized mouse model for liver disease research. The session emphasized novel biochemical pathways and therapeutic insights, offering promising directions for further study and clinical applications in liver disease management.

Keywords

liver disease research

portal hypertension

hepatocellular carcinoma

fibrosis management

immune evasion

therapeutic targets