The Liver Meeting 2023-MASLD and Pediatric SIG: MAFLD from Tweens to Twenties Pt 2

Video Transcription

Video Summary

Metabolic bariatric surgeries like sleeve gastrectomy and Roux-en-Y gastric bypass are effective and safe treatments for adolescents with severe obesity and metabolic diseases. These surgeries lead to significant weight loss and resolution of comorbidities, with comparable safety and efficacy across age groups. Although there are risks of weight regain and nutritional deficiencies, the benefits in improving metabolic health and quality of life are substantial. Post-surgery monitoring for bone health, reflux, and alcohol use is crucial for long-term success.<br /><br />There is a need to increase the utilization of metabolic bariatric surgeries in eligible youth due to current underutilization. Challenges such as patient ambivalence, fear of surgery, and lack of referrals hinder access to these procedures. The discussion also covered muscle distribution differences, prevalence of metabolic-associated fatty liver disease (MAFLD) in pediatric populations, and potential non-invasive biomarkers for pediatric MAFLD trials. Despite limited data on the natural history and outcomes of these diseases, it was recognized that pediatric MAFLD carries serious health risks. More research, including qualitative studies to understand patient perspectives and enhance treatment uptake in adolescents, is essential.

Keywords

Metabolic bariatric surgeries

Sleeve gastrectomy

Roux-en-Y gastric bypass

Adolescents

Severe obesity

Metabolic diseases

Weight loss

Comorbidities resolution

Post-surgery monitoring

Metabolic health

Quality of life