The Liver Meeting 2023-Hyman J. Zimmerman State of the Art: New Diagnostic Approaches in Acetaminophen Acute Liver Injury

Hyman J. Zimmerman State of the Art: New Diagnostic Approaches in Acetaminophen Acute Liver Injury

Video Transcription

Video Summary

Dr. Laura James, a renowned pediatric pharmacologist, presented the ASLD state-of-the-art High Zimmerman hepatotoxicity lecture of 2023, focusing on acetaminophen liver injury detection. With three decades of research on acetaminophen toxicity, she co-founded ATD LLC to develop Acetastat, a rapid acetaminophen toxicity detection test. Her studies highlight the importance of interdisciplinary team science and translational research in diagnosing acetaminophen liver injury. Collaborating with the Acute Liver Failure Study Group, her research demonstrated the effectiveness of detecting acetaminophen adducts in patients, leading to the development of acetastat for clinical use. Through grants from NIDDK, her work with DCN Diagnostics has progressed towards FDA approval, aiming for a definitive clinical study by the end of 2024.

Keywords

Dr. Laura James

pediatric pharmacologist

ASLD state-of-the-art High Zimmerman hepatotoxicity lecture

acetaminophen liver injury detection

Acetastat

acetaminophen toxicity detection test