The Liver Meeting 2023-Acute On Chronic Liver Failure SIG

Video Transcription

Video Summary

The video discussed acute-on-chronic liver failure (ACLF) with experts covering kidney failure, sepsis, septic shock, and neurologic failure. Dr. Nourand highlighted ACLF criteria, the importance of distinguishing kidney dysfunction types, and early recognition of kidney issues. Dr. O'Leary emphasized infection's impact on ACLF and discussed septic shock management. Dr. Pringle-Bloom covered hepatic encephalopathy and its treatment. Additionally, the importance of kidney, liver transplantation, and post-transplant care were addressed. Early planning and honest discussions were emphasized, showing ACLF with brain failure didn't predict post-transplant death. Therapies like FMT and MARS were discussed, as well as the use of point-of-care ultrasound and urinary biomarkers to differentiate between conditions. Other topics included reducing albumin overuse, role of l-olol in encephalopathy management, and personalized, early, and multidisciplinary approach to treating ACLF patients.

Keywords

acute-on-chronic liver failure

ACLF criteria

kidney dysfunction

sepsis

septic shock

neurologic failure

infection impact on ACLF

hepatic encephalopathy

kidney transplantation

liver transplantation

post-transplant care

FMT and MARS therapies