The Liver Meeting 2023-3065 - Cirrhosis As a Multisystem Disorder

Video Transcription

Video Summary

In the video transcript, Dr. Carvelas discusses the critical care management of acute and chronic liver failure, particularly focusing on indications for ICU transfer, volume status assessment, respiratory failure, renal replacement therapy, prognosis with and without liver transplant, and the use of multi-organ failure scores. He emphasizes the importance of early appropriate antimicrobial therapy for sepsis, baseline assessment of volume and perfusion for circulatory failure, a lung-protective strategy for respiratory failure, and the preference for continuous renal replacement therapy in ACLF patients. Dr. Fallon adds insights on cirrhotic cardiomyopathy, carbidolol use in complications, and considerations in liver transplantation for cirrhotic cardiomyopathy. Dr. Biggins addresses issues with diuretics post-recovery from AKI, the use of tips in improving GFR, and the potential use of terlipressin in impacting MELD scores. The conversation also touches on the challenges of high-cost medications like terlipressin, alternative treatment options, and balancing risks of pulmonary remodeling in patients awaiting transplant.

Keywords

critical care management

liver failure

ICU transfer

renal replacement therapy

liver transplant

cirrhotic cardiomyopathy

terlipressin