The Liver Meeting 2023-3064 - Cirrhosis As a Multisystem Disorder

Video Transcription

Video Summary

In the post-grad course video transcript, session two focused on the cross-talk between the immune system and gut-brain axis. The session was moderated by Dr. Jalan from University College London and Dr. Szabo from Harvard Medical School. The discussion highlighted the case of a 56-year-old male with alcohol-associated liver disease presenting with ascites and difficulty sleeping. The patient's labs and imaging results were discussed, along with questions about insomnia treatment, infection prevention, and further evaluation for liver lesion. The transcript delved into the immune deficiency in cirrhosis, the gut-liver-brain axis, and potential therapies for immune deficiency. Dr. Murrow from Inserm Paris discussed the immune effects of cirrhosis and potential therapies. Dr. Jasbah Raj from the Medical College of Virginia talked about the clinical implications of the gut-liver-brain axis, emphasizing the complexity of cognitive complaints in cirrhosis patients and the need for individualized treatment approaches, including considerations for alcohol use disorder, sleep issues, and microbial signatures. The transcript highlighted the importance of personalized care and utilizing microbial data in treatment decisions.

Keywords

post-grad course

immune system

gut-brain axis

alcohol-associated liver disease

cirrhosis

individualized treatment

microbial data