The Liver Meeting 2023-3063 - Cirrhosis As a Multisystem Disorder

Video Transcription

Video Summary

In the TLM 2023 postgraduate course organized by Ray Kim, the focus was on cirrhosis as a multisystem disorder due to the increasing impact of liver disease globally. The course emphasized the importance of managing cirrhosis and its complications for patient wellbeing. Natalie Torok and Sumit Asrani were tasked with running the course. Topics such as the global burden of liver disease, including the prevalence of cirrhosis and non-viral liver disease, were discussed. The speakers highlighted the genetic predisposition, aging, epigenetics, and lifestyle factors affecting the progression of liver disease. Factors like biological aging and senescent cells were identified as accelerators of fibrosis progression. Interventions such as weight loss and bariatric surgery were shown to reverse liver degeneration and fibrosis, offering hope for disease management and prevention of complications. The course emphasized the importance of considering social determinants of health and implementing lifestyle modifications to improve patient outcomes.

Keywords

cirrhosis

liver disease

genetic predisposition

fibrosis progression

weight loss

bariatric surgery

social determinants of health

patient outcomes