The Liver Meeting 2022-Hepatitis Debrief

Video Transcription

Video Summary

Dr. Joseph Lin from the Yale School of Medicine presented a summary of impactful abstracts related to viral hepatitis. The first abstract discussed the global incidence of Hepatitis B, which is still significant, particularly in low and middle-income countries in Africa and Asia. The second abstract focused on the possibility of reducing vertical transmission of Hepatitis B by removing Hepatitis B immunoglobulin and extending the duration of tenofovir treatment during pregnancy. The study showed that the regimen without HBIG may be safe and effective for this population. Another abstract examined the risk of hepatocellular carcinoma (HCC) in patients with low levels of Hepatitis B viral load. The study found that even low levels of viremia were associated with an increased risk of HCC. Other abstracts discussed topics such as Hepatitis B integration in patients with functional cure, the correlation between integrated DNA and surface antigen levels in chronic Hepatitis B patients, predictors of achieving very low levels of surface antigen, and the role of boulevertide and functional cure in chronic Hepatitis Delta infection. The summary also highlighted the challenges in achieving hepatitis elimination targets and the risk of reinfection after successful treatment for Hepatitis C.

Keywords

Hepatitis B

vertical transmission

Hepatitis B immunoglobulin

hepatocellular carcinoma

Hepatitis B viral load

reinfection