Hans Popper State-of-the-Art Lecture
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Presented by Dr. Takanori Takebe, MD, Pediatrics, Cincinnati Children's Hospital Medical Center

The goal of this program is to propose integrative pre-clinical research concept for human NAFLD/NASH, combining patients’ and engineered human tissues using emerging technologies such as induced pluripotency, organoids, gene editing and comprehensive genomics. By introducing population-based organoid system, this investigative strategy may open the door to the studies of pleiotropic factors, potentially transforming the future of precision hepatology.
Human liver organoids
Drug development
Liver tissue renewal
Non-alcoholic fatty liver disease
Genetic variants
Treatment response
Complex models
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