The Liver Meeting 2020-Pediatric Liver Disorders SIG & Portal Hypertension SIG - Part 1 Controversies in the Diagnosis and Management of Non-cirrhotic Portal Hypertension in Children and Adults

Pediatric Liver Disorders SIG & Portal Hypertension SIG - Part 1 Controversies in the Diagnosis and Management of Non-cirrhotic Portal Hypertension in Children and Adults

Back to course

Video Transcription

Video Summary

The video discusses controversies in defining non-cerebral portal hypertension and its diagnostic approach, emphasizing differences from cirrhosis. Various causes, manifestations, genetic mutations like KCNN3 and DGO kappa, and imaging findings for portal vein thrombosis are explored. A case study details a 12-year-old female with symptoms indicating portal hypertension without cirrhosis, confirmed through imaging, liver biopsy, and thrombophilia workup. The importance of a comprehensive investigation, genetic testing, HVPG measurement, and liver biopsy by experts is highlighted for accurate diagnosis and management. The need for further research to understand the underlying causes of non-cirrhotic portal hypertension is emphasized.

Keywords

non-cerebral portal hypertension

diagnostic approach

cirrhosis differences

causes

manifestations

genetic mutations

KCNN3

DGO kappa

imaging findings

portal vein thrombosis

case study

12-year-old female