The Liver Meeting 2019-Primary Biliary Cholangitis Practice Guidance 2018

Primary Biliary Cholangitis Practice Guidance 2018

Video Transcription

Video Summary

The video transcript discusses updated guidance on primary biliary cholangitis (PBC) and emphasizes the importance of early diagnosis and treatment. PBC predominantly affects women, with prevalence increasing over time. Diagnosis requires specific criteria such as cholestasis, autoantibodies, or liver biopsy. Ursodeoxycholic acid is the main therapy, with newer options like abetacolic acid showing promise. Monitoring is crucial, including liver function tests, thyroid function, bone density, and cancer surveillance. Complications such as osteopenia, fat-soluble vitamin deficiencies, and lipid abnormalities are common and require management. Liver transplantation may still be necessary in some cases. The transcript highlights the benefits of surveillance in improving patient outcomes and mentions potential future therapies like fibrates. Early intervention is key to improving prognosis in PBC patients.

Asset Caption

Presenter: Keith D. Lindor

Keywords

primary biliary cholangitis

early diagnosis

treatment

ursodeoxycholic acid

monitoring

complications