The Liver Meeting 2019-Prevention of Ascites in Cirrhosis: What's New?

Prevention of Ascites in Cirrhosis: What's New?

Video Transcription

Video Summary

The speaker discussed the relationship between portal hypertension and ascites in patients with cirrhosis. They explained that portal hypertension drives ascites formation by increasing sinusoidal pressure. The main mechanism for ascites was shown to be an increase in sinusoidal pressure. Studies revealed that decreasing portal pressure can reduce ascites development. Treatment options include non-selective beta blockers, statins, tips procedures, and antibiotics to target bacterial translocation. The speaker highlighted the importance of managing portal pressure to prevent and improve outcomes for ascites in both compensated and decompensated patients. Therapies targeting inflammation and using albumin infusions were also discussed as potential interventions for ascites management.

Asset Caption

Presenter: Guadalupe Garcia-Tsao

Keywords

portal hypertension

ascites

cirrhosis

sinusoidal pressure

treatment options