The Liver Meeting 2019-Precision Medicine to Guide Therapy in Liver Cancer

Video Transcription

Video Summary

The presentation discusses using precision medicine for guiding therapy in liver cancer, focusing on the importance of tumor biopsies to understand diagnosis, molecular features, and prognosis in patients with liver masses. The speaker presents a case study of a 61-year-old man with an unusual liver mass, emphasizing the need for multidisciplinary discussions and biopsies to determine the nature of the lesion. The transcript delves into the molecular classification of hepatocellular carcinoma (HCC) and cholangiocarcinoma, highlighting different subgroups and their implications for treatment. It also mentions approved systemic therapies for advanced liver cancer, such as sorafenib and lembatinib for HCC. The presentation touches on the potential of biomarkers to predict responses to checkpoint inhibitors and the role of liquid biopsies in cancer detection and precision oncology. Overall, the transcript underscores the importance of personalized approaches in managing liver cancer based on individual molecular profiles.

Asset Caption

Presenter: Joseph Llovet

Keywords

precision medicine

liver cancer

tumor biopsies

molecular classification

systemic therapies

liquid biopsies