The Liver Meeting 2019-Overview of Bile Acid Receptors

Video Transcription

Video Summary

The speaker provided an overview of bioacids and their receptors during a scientific session. Bioacids originate from cholesterol and are crucial for lipid absorption and energy metabolism. They are conjugated by glycine or taurine and can be modified by gut bacteria. Different receptors like FXR, TGR5, and S1PR2 have specific roles in various cells. Studies have shown potential for bioacid receptor targeting in treating diseases. The presentation emphasized the importance of understanding cell-specific functions and developing mouse models with humanized bioacid pools for research. Further research is needed to explore the long-term effects of targeting bioacid receptors.

Asset Caption

Presenter: Huiping Zhou

Keywords

bioacids

receptors

cholesterol

lipid absorption

gut bacteria