The Liver Meeting 2019-Epidemiology of Obesity, Diabetes and HCC World Wide

Epidemiology of Obesity, Diabetes and HCC World Wide

Video Transcription

Video Summary

The video transcript discusses the global epidemiology of obesity, diabetes, and hepatocellular carcinoma (HCC). It highlights the changing trends where traditionally high-incidence areas of HCC are declining, while low-incidence areas are increasing, mainly due to factors like obesity and diabetes. The speaker emphasizes the importance of understanding the proximal associations between metabolic risk factors like abdominal obesity, diabetes, and NAFLD in relation to HCC risk. While the relative risk associated with metabolic syndrome is modestly elevated, the absolute risk remains low. The transcript suggests that as hepatitis C and hepatitis B prevalence decreases, the incidence of NAFLD-related HCC may increase in the future. The discussion also touches on the significance of cirrhosis, genetic predisposition, and the need for further research on risk stratification and treatment effects.

Asset Caption

Presenter: Hashem B. El-Serag

Keywords

global epidemiology

obesity

diabetes

hepatocellular carcinoma

metabolic risk factors

NAFLD