The Liver Meeting 2019-Clinical Models and Risk Assessment: Acute-on-Chronic Liver Failure as a Paradigm

Clinical Models and Risk Assessment: Acute-on-Chronic Liver Failure as a Paradigm

Video Transcription

Video Summary

The speaker discusses acute on chronic liver failure (ACLF) in patients like Mr. Smith, emphasizing its distinction from acute hepatic decompensation. Three clinical prediction models for ACLF severity and prognosis are presented: APASL-ACLF, ESL-CLIF, and NACCELD, highlighting similarities and differences in components. These models help stratify patients by organ system dysfunction to predict mortality risk more accurately than traditional measures like MELD score. The speaker demonstrates how applying these models to patients like Mr. Smith can guide clinical decisions, highlighting the importance of precision hepatology in providing personalized care based on objective data. The discussion stresses the utility of clinical prediction models in refining risk assessment, facilitating treatment decisions, and enabling tailored discussions with patients and families for improved outcomes.

Asset Caption

Presenter: Jennifer C. Lai

Keywords

acute on chronic liver failure

APASL-ACLF

ESL-CLIF

NACCELD

clinical prediction models