The Liver Meeting 2019-Autoimmune Liver Disease in Younger Patient: Crossing Phenotypic Boundaries*

Autoimmune Liver Disease in Younger Patient: Crossing Phenotypic Boundaries*

Video Transcription

Video Summary

The speaker discusses a case of a 12-year-old boy with autoimmune hepatitis and presents insights into distinguishing phenotypes of autoimmune liver diseases in pediatrics. Emphasizing the challenges in diagnosing conditions like autoimmune hepatitis in children with non-alcoholic fatty liver disease, primary sclerosing cholangitis, or primary immunodeficiencies. They also review genetic predispositions, predictors for therapy response, and the importance of early detection of biliary diseases. The presentation highlights the significance of precision medicine tools, diagnostic modalities like MRCP, and the need for further research on circulating biomarkers. The talk concludes by underscoring the necessity of collaborative efforts for validating predictors in individualized therapy for pediatric autoimmune liver diseases.

Asset Caption

Presenter: Alexander Miethke

Keywords

autoimmune hepatitis

pediatrics

phenotypes

non-alcoholic fatty liver disease

genetic predispositions

precision medicine